1-(2-FLUOROBIPHENYL-4-YL)-ALKYL CARBOXYLIC ACID DERIVATIVES FOR THE THERAPY OF TRANSTHYRETIN AMYLOIDOSIS 1-(2--4-)-
摘要
Derivatives of 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid are capable of stabilizing the tetrameric native state of transthyretin for the prophylaxis and treatment of amyloidosis.
申请公布号
HK1174609(A1)
申请公布日期
2016.05.06
申请号
HK20130101930
申请日期
2013.02.15
申请人
CHIESI FARMACEUTICI S.P.A.
发明人
IMBIMBO, BRUNO, PIETRO BP;VILLETTI, GINO G;BERNI, RODOLFO R
