发明名称 IMPROVEMENT OF THE BIOAVAILABILITY OF ACTIVE SUBSTANCES HAVING AN AMIDINE FUNCTION IN MEDICAMENTS
摘要 The invention relates to the use of N,N'-dihydroxyamidine (I), N,N'-dihydroxyamidine ether (II), N,N'-dihydroxyamidine diether (III), N,N'-dihydroxyamidine ester (IV), N,N'-dihydroxyamidine diester (V) or 4-hydroxy-1,2,4-oxadiazoline (VI) of the formulae cited above, wherein R represents hydrogen, an alkyl and/or aryl radical, as a substitute for an amidine function of a medicament for improving the bioavailability of the medicament.
申请公布号 HK1210694(A1) 申请公布日期 2016.05.06
申请号 HK20150111410 申请日期 2015.11.19
申请人 DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MB 发明人 CLEMENT, BERND B;REEH, CHRISTIANE C
分类号 A61K;A61P 主分类号 A61K
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