AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF
摘要
The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.
申请公布号
WO2016035007(A3)
申请公布日期
2016.05.06
申请号
WO2015IB56630
申请日期
2015.09.01
申请人
UNICHEM LABORATORIES LIMITED
发明人
SATHE, DHANANJAY D;DAS, ARIJIT;SURVE, YASHWANT;AHIRE, RAMDAS N.;KHANDEKAR, AMIT C.