发明名称 |
INJECTABLE BUPRENORPHINE FORMULATION |
摘要 |
The present invention provides an injectable liquid formulation with controlled release comprising: • a) a lipid controlled-release matrix comprising at least 50% triacyl lipids; • b) at least one oxygen containing organic solvent; • c) at least 16% by weight of at least one active agent selected from buprenorphine and salts thereof, calculated as buprenorphine free base. The invention also provides a method for the treatment of pain, for opioid maintenance therapy or for the treatment of opioid dependence by detoxification and/or maintenance or for the treatment or prophylaxis of the symptoms of opioid withdrawal and/or cocaine withdrawal by injecting such a liquid composition. |
申请公布号 |
WO2016066655(A1) |
申请公布日期 |
2016.05.06 |
申请号 |
WO2015EP74901 |
申请日期 |
2015.10.27 |
申请人 |
CAMURUS AB |
发明人 |
TIBERG, FREDRIK;JOHNSSON, MARKUS;HARWIGSSON, IAN |
分类号 |
A61K9/08;A61K31/485 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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