| 发明名称 |
THIOPHENE AND THIAZOLE SUBSTITUTED TRIFLUOROETHANONE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS |
| 摘要 |
The present invention relates to the use of trifluoroacetylated lysine (Boc-L-Lys(epsilon- trifluoroacetyl)-MCA) as a substrate for histone deacetylases, specific for the class Ha subtype. |
| 申请公布号 |
EP1926721(B1) |
申请公布日期 |
2016.05.04 |
| 申请号 |
EP20060779628 |
申请日期 |
2006.09.05 |
| 申请人 |
MSD ITALIA S.R.L. |
发明人 |
FERRIGNO, FEDERICA;JONES, PHILIP;MURAGLIA, ESTER;ONTORIA ONTORIA, JESUS MARIA;SCARPELLI, RITA |
| 分类号 |
C07D333/38;A61K31/381;A61K31/426;A61P25/18;A61P25/28;A61P35/00;C07D277/56;C07D333/34;C07D409/08;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;C07D471/18;C07D487/04;C07D487/08;C07D487/18;C07D491/10;C07D495/04;C12Q1/34 |
主分类号 |
C07D333/38 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
