发明名称 PHARMACEUTICAL COMPOSITION COMPRISING ANTI CAPRIN-1 ANTIBODIES FOR TREATING AND/OR PREVENTING CANCER
摘要 According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody or a fragment thereof as an active ingredient having immunological reactivity with a partial polypeptide of CAPRIN-1, which is represented by any of even-numbered sequences of SEQ ID NOS: 2 to 30, wherein the polypeptide has the amino acid sequence represented by SEQ ID NO: 37 or an amino acid sequence having 80% or more sequence identity with the amino acid sequence represented by SEQ ID NO: 37.
申请公布号 EP2532364(B1) 申请公布日期 2016.05.04
申请号 EP20110739865 申请日期 2011.02.04
申请人 TORAY INDUSTRIES, INC. 发明人 SAITO TAKANORI;OKANO FUMIYOSHI;KOBAYASHI SHINICHI
分类号 A61K39/395;A61P35/00;A61P35/02;C07K16/30 主分类号 A61K39/395
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