| 发明名称 |
COLORIMETRIC AND FLUORESCENT PROTEINS |
| 摘要 |
The invention relates to intracellular lipid binding proteins that bind retinoids and/or dye ligands and that are modified to transmit or emit light at a variety of different wavelengths. |
| 申请公布号 |
US2016115210(A1) |
申请公布日期 |
2016.04.28 |
| 申请号 |
US201514883944 |
申请日期 |
2015.10.15 |
| 申请人 |
Board of Trustees of Michigan State University |
发明人 |
Borhan Babak;Geiger James;Wang Wenjing;Vasileiou Chrysoula;Lee Kin Sing;Berbasova Tetyana |
| 分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated nucleic acid encoding a modified polypeptide selected from a member of the intracellular lipid binding protein family, wherein the modified polypeptide transmits or emits light when bound to a retinoid or fluorescent dye molecule, and wherein the intracellular lipid binding protein has been modified so that an amino acid at any of positions 102-135 can form a Schiff base with a retinoid. |
| 地址 |
East Lansing MI US |
