| 发明名称 |
BROMODOMAIN INHIBITORS |
| 摘要 |
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease. |
| 申请公布号 |
US2016115134(A1) |
申请公布日期 |
2016.04.28 |
| 申请号 |
US201514789881 |
申请日期 |
2015.07.01 |
| 申请人 |
Quanticel Pharmaceuticals, Inc. |
发明人 |
Bennett Michael John;Stafford Jeffrey Alan |
| 分类号 |
C07D217/24;C07D471/04;C07D405/04;C07D401/04;C07D213/64;C07D241/20;C07D213/73;C07D213/74;C07D487/04;C07D237/14;C07D401/14;C07D239/54;C07D239/56;C07D417/14;C07D405/12;C07D409/04;C07D403/04;C07D498/04;C07D413/06;C07D491/048;C07D495/04;C07D413/04 |
主分类号 |
C07D217/24 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
San Diego CA US |
