发明名称 |
ROPINIROLE-CONTAINING ADHESIVE PATCH |
摘要 |
A patch containing free ropinirole (ropinirole in free form) in an adhesive base is provided, in which the patch exhibits favorable and continuous transdermal absorbability, high drug stability, and excellent adhesiveness. A transdermal absorption patch includes free ropinirole added to an adhesive base that contains a styrene-isoprene-styrene block copolymer (SIS), one or two or more tackifier resins containing a rosin-based resin, and a softener. The transdermal absorption patch is characterized in that the compounding ratio of the rosin-based resin to the free ropinirole represented as the ratio of the weight of the combined rosin-based resin to the free ropinirole is 3.5 to 8.0. In particular, a ropinirole-containing patch wherein the rosin-based resin is a hydrogenated rosin glycerol ester and the softener is liquid paraffin is provided. |
申请公布号 |
EP2926814(A4) |
申请公布日期 |
2016.04.27 |
申请号 |
EP20130858468 |
申请日期 |
2013.11.28 |
申请人 |
TEIKOKU SEIYAKU CO., LTD. |
发明人 |
INOO, KATSUYUKI;KATAYAMA, AKIKO;TAKANO, DAIKI |
分类号 |
A61K31/4045;A61K9/70;A61K47/06;A61K47/14;A61K47/32;A61P25/16 |
主分类号 |
A61K31/4045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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