发明名称 |
ARTIFICIAL SKIN TISSUE, ARTIFICIAL SKIN MODEL AND MANUFACTURING METHOD THEREFOR |
摘要 |
Provided is a novel method capable of manufacturing an artificial skin model including dendritic cells. A method for manufacturing an artificial skin model includes the following: forming a dermal tissue layer by culturing coated cells in which a cell surface is coated with a coating film containing an extracellular matrix component, so that the coated cells are layered; forming a basal layer including type IV collagen on the dermal tissue layer by bringing type IV collagen into contact with the dermal tissue layer; and forming an epidermal layer by arranging epidermal cells on the basal layer. At least one of the dermal tissue layer and the epidermal layer includes dendritic cells. |
申请公布号 |
EP2894219(A4) |
申请公布日期 |
2016.04.27 |
申请号 |
EP20130834839 |
申请日期 |
2013.09.04 |
申请人 |
OSAKA UNIVERSITY;BIOMEDICAL TECHNOLOGY HYBRID CO., LTD. |
发明人 |
AKASHI, MITSURU;MATSUSAKI, MICHIYA;NAWANO, MASAAKI;HASHIMOTO, KOJI;SHIRAKATA, YUJI |
分类号 |
A61L27/60;A61L27/36;A61L27/38;C12N1/00;C12N5/07;C12N5/0784 |
主分类号 |
A61L27/60 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|