发明名称 |
SEQUENCE CONVERSION AND SIGNAL AMPLIFIER DNA HAVING POLY DNA SPACER SEQUENCES AND DETECTION METHODS USING SAME |
摘要 |
Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide. Also disclosed are methods for detecting a target nucleic acid in a sample in which said sample is contacted, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide and a signal amplifier oligonucleotide. The disclosure also provides compositions and kits comprising such sequence conversion and signal amplifier oligonucleotides. |
申请公布号 |
WO2016059474(A2) |
申请公布日期 |
2016.04.21 |
申请号 |
WO2015IB02145 |
申请日期 |
2015.10.13 |
申请人 |
ABBOTT JAPAN CO., LTD;TOKYO INSTITUTE OF TECHNOLOGY |
发明人 |
KOMIYA, KEN;KOMORI, MAKOTO;YOSHIMURA, TORU |
分类号 |
C12Q1/68;C12Q1/34;C12Q1/48 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|