发明名称 |
STABLE AND WATER SOLUBLE PHARMACEUTICAL COMPOSITIONS COMPRISING PEMETREXED |
摘要 |
The present invention relates to a solid pharmaceutical composition comprising pemetrexed and a solubilizing amount of meglumine or tromethamine. The composition is sufficiently stable for purpose of making pharmaceutical formulations, particularly lyophilized formulations, and is sufficiently soluble in water for purposes of using in parenteral administration. |
申请公布号 |
EP3007681(A1) |
申请公布日期 |
2016.04.20 |
申请号 |
EP20130728423 |
申请日期 |
2013.06.14 |
申请人 |
SYNTHON B.V. |
发明人 |
ZALUDEK, BOREK;EUPEN VAN, JACOBUS THEODORUS HENRICUS |
分类号 |
A61K9/19;A61K31/519;A61K47/18 |
主分类号 |
A61K9/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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