摘要 |
The present disclosure relates to compounds of formula (I): which are inhibitors of p38 mitogen-activated protein kinase enzymes, particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD. |
申请人 |
RESPIVERT LIMITED |
发明人 |
ITO, KAZUHIRO;STRONG, PETER;RAPEPORT, WILLIAM, GARTH;MURRAY, PETER, JOHN;KING-UNDERWOOD, JOHN;WILLIAMS, JONATHAN GARETH;ONIONS, STUART, THOMAS;JOLY, KEVIN;CHARRON, CATHERINE, ELISABETH |