发明名称 Insoluble dietary fiber-containing product derived from grain seeds
摘要 This invention provides a product safe for treating, improving or preventing an inflammatory bowel disease such as ulcerative colitis, and provides a product comprising an insoluble dietary fiber obtained by enzymatic treatment of seeds of a grain plant(s) or germinated young seeds thereof, as well as a food or drink or medicament comprising the product.
申请公布号 US9314496(B2) 申请公布日期 2016.04.19
申请号 US200812809191 申请日期 2008.12.19
申请人 KIRIN HOLDINGS KABUSHIKI KAISHA 发明人 Ohmae Hideo;Murayama Hiroshi;Takimoto Naohiro;Sakamoto Yuji;Kanauchi Osamu;Katayama Mikio;Watanabe Hiroyuki;Komano Yuta
分类号 A61K35/00;A61K36/899;A23L1/10;A23L1/105;A23L1/308;C12P19/04;C12P19/14 主分类号 A61K35/00
代理机构 Sughrue Mion, PLLC 代理人 Sughrue Mion, PLLC
主权项 1. A method for the treatment or prevention of ulcerative colitis, said method comprising administering a therapeutically-effective amount of an insoluble dietary fiber-containing product to a subject in need thereof, wherein the insoluble dietary fiber-containing product has 90% or more of the aleurone layer removed and wherein said product is derived from seeds of a Gramineae plant(s) and produced by a process comprising the following steps of: (a) preparing a raw-material by pulverizing or polishing the seeds of the Gramineae plant(s) then recovering the obtained outer fraction of the seeds; (b) subjecting the raw material to a starch removing treatment to prepare a starch free fraction; (c) enzymatically treating the fraction prepared in the step (b) with an enzyme having hemicellulase activity; and (d) recovering the insoluble fraction containing insoluble dietary fibers from the enzymatically treated fraction produced by step (c).
地址 Tokyo JP