发明名称 |
FREMSTILLING AF MIKROBIEL OLIE, DER INDEHOLDER FLERUMÆTTEDE FEDTSYRER |
摘要 |
The present invention provides a process for the production of a microbial oil comprising culturing a micro-organism in a two stage fermentation process where, in a last stage that precedes the end of fermentation, the carbon source is: consumed by the micro-organisms at a rate greater than it is added to the medium; added at a rate # 0.30 M carbon/kg medium; or is rate limiting on the growth of the micro-organism. The micro-organisms thus have the carbon source restricted so that they preferentially metabolise fats or lipids other than arachidonic acid (ARA), so increasing the proportion of ARA in the cells. A microbial oil is then recovered from the micro-organism, using hexane as a solvent, that has at least 50% ARA and at least 90% triglycerides. |
申请公布号 |
DK1513941(T3) |
申请公布日期 |
2016.04.18 |
申请号 |
DK20030740299T |
申请日期 |
2003.06.20 |
申请人 |
DSM IP ASSETS B.V. |
发明人 |
STREEKSTRA, HUGO;BROCKEN, PETRUS, JOSEPH, MARIA |
分类号 |
C12P7/64;A23D9/00;A23D9/007;A23D9/02;A23K1/16;A23L1/28;A23L1/30;A61K8/67;A61K8/92;A61K8/99;A61K31/202;A61K35/74;A61P25/00;A61P43/00;A61Q19/00;C11B1/10;C11C3/00;C12N1/00;C12N1/12;C12N1/14;C12N1/16;C12N1/20;C12R1/645 |
主分类号 |
C12P7/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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