发明名称 |
ASSAY TIL METHYLERING I GST-PI-GENET |
摘要 |
A diagnostic or prognostic assay is disclosed for a disease or condition characterised by abnormal methylation of cytosine at a site or sites within the glutathione-S-transferase (GST) Pi gene and/or its regulatory flanking sequences (e.g. prostate cancer and liver cancer). The assay comprises;
(i) isolating DNA from said subject, and
(ii) determining (e.g. by selective PCR amplification) the presence of abnormal methylation of cytosine at a site or sites within the GST-Pi gene and/or its regulatory flanking sequences. |
申请公布号 |
DK2357256(T3) |
申请公布日期 |
2016.04.18 |
申请号 |
DK20100185706T |
申请日期 |
1999.04.23 |
申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION |
发明人 |
CLARK, SUSAN JOY;MILLAR, DOUGLAS S.;MOLLOY, PETER LAURENCE |
分类号 |
C12N15/09;C12Q1/68;C12N9/10;C12N15/54;C12Q1/48 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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