发明名称 |
Composición farmacéutica líquida que comprende nitisinona |
摘要 |
The invention concerns a liquid pharmaceutical formulation suitable for oral administration, comprising a suspension of an effective amount of micronized 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (nitisinone); and citric acid buffer having a pH in the range of 2.5 to 3.5. The formulation is useful in the treatment of disorders and diseases in which inhibition of 4-hydroxyphenylpyruvate dioxygenase (HPPD) is desirable, e.g. in hereditary tyrosinaemia type I. |
申请公布号 |
ES2566787(T3) |
申请公布日期 |
2016.04.15 |
申请号 |
ES20120802262T |
申请日期 |
2012.06.20 |
申请人 |
Swedish Orphan Biovitrum International AB |
发明人 |
SVENSSON, Lennart;SIDEN, Hans |
分类号 |
A61K9/10;A61K31/122;A61P3/00 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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