发明名称 SPIRODIAMINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS
摘要 The invention provides compounds having the general formula (I) pharmaceutical compositions containing the compounds and a process for their preparation. The compounds act as aldosterone synthase inhibitors and are for use in the treatment or prevention of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrom.
申请公布号 WO2016055394(A1) 申请公布日期 2016.04.14
申请号 WO2015EP72887 申请日期 2015.10.05
申请人 F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. 发明人 AEBI, JOHANNES;AMREIN, KURT E.;CHEN, JUNLI;HORNSPERGER, BENOIT;KUHN, BERND;LIU, YONGFU;LI, DONGBO;MAERKI, HANS PETER;MARTIN, RAINER E.;MAYWEG, ALEXANDER;TAN, XUEFEI;WU, JUN;YU, JIANHUA
分类号 C07D471/10;A61K9/20;A61K31/4439;A61K31/444;A61K31/4725;A61P5/42;A61P9/04;A61P9/12;A61P13/12;C07D487/10;C07D519/00 主分类号 C07D471/10
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