发明名称 |
ISOLATION OF SOLUBLE PROTEINS FROM AGGREGATED CASEIN-CONTAINING MIXTURES |
摘要 |
The present invention relates to a method for separating at least one soluble protein fraction from an aggregated casein-containing material, the method comprises the steps of: (i) providing the aggregated casein-containing material; (ii) Contacting the aggregated casein-containing material with a chromatographic support allowing one or more soluble protein(s) present in the aggregated casein-containing material to be retained by the chromatographic support; (iii) Obtaining a permeate fraction from the chromatographic support comprising aggregated casein; (iv) Optionally washing the chromatographic support; (v) Subjecting the chromatographic support to at least one elution buffer obtaining at least one soluble protein fraction from the chromatographic support; and wherein the chromatographic support comprises one or more mixed-mode ligands capable of binding the soluble proteins from the aggregated casein-containing material. |
申请公布号 |
WO2016055064(A2) |
申请公布日期 |
2016.04.14 |
申请号 |
WO2015DK00039 |
申请日期 |
2015.10.06 |
申请人 |
UPFRONT CHROMATOGRAPHY A/S |
发明人 |
LIHME, ALLAN OTTO FOG;HANSEN, MARIE BENDIX |
分类号 |
A23C9/146 |
主分类号 |
A23C9/146 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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