Unit dosage forms of meloxicam containing either 5 mg or 10 mg of meloxicam that provide effective pain relief and have desirable pharmacokinetic properties are described. The unit dosage forms can provide pain relief when a single unit dose is administered to a patient and useful for treating pain such as osteoarthritis pain at a relatively low systemic exposure to meloxicam.
申请公布号
US2016101110(A1)
申请公布日期
2016.04.14
申请号
US201514974108
申请日期
2015.12.18
申请人
ICEUTICA PTY LTD.
发明人
Bosch H. William
分类号
A61K31/5415;A61K9/14
主分类号
A61K31/5415
代理机构
代理人
主权项
1. A unit dosage form of a pharmaceutical composition comprising 5 mg of meloxicam, wherein a single dose, upon oral administration to a population of healthy adults in the fasted state, provides a mean plasma AUC (0-∞) of 7500-20000 h*ng/ml.