发明名称 COMBINATION THERAPY OF BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5 AND CHEMOTHERAPEUTIC AGENTS
摘要 The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, and in particular to combination therapies employing such bispecific antibodies and a chemotherapeutic agent, and their use of these combination therapies for the treatment of cancer.
申请公布号 WO2016055432(A2) 申请公布日期 2016.04.14
申请号 WO2015EP72974 申请日期 2015.10.06
申请人 F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. 发明人 FRIESS, THOMAS;KRIETER, OLIVER;MAJETY, MEHER;WARTHA, KATHARINA
分类号 C07K16/22 主分类号 C07K16/22
代理机构 代理人
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