发明名称 |
COMBINATION THERAPY OF BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5 AND CHEMOTHERAPEUTIC AGENTS |
摘要 |
The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, and in particular to combination therapies employing such bispecific antibodies and a chemotherapeutic agent, and their use of these combination therapies for the treatment of cancer. |
申请公布号 |
WO2016055432(A2) |
申请公布日期 |
2016.04.14 |
申请号 |
WO2015EP72974 |
申请日期 |
2015.10.06 |
申请人 |
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. |
发明人 |
FRIESS, THOMAS;KRIETER, OLIVER;MAJETY, MEHER;WARTHA, KATHARINA |
分类号 |
C07K16/22 |
主分类号 |
C07K16/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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