A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The topiramate retains its taste-masked form after dispersion in the mouth of a subject even though the particles are not coated with a polymeric material. The dosage form disperses in saliva or water in less than 2 min even though it has a high content of wax. It can be used to treat diseases or disorders that are therapeutically responsive to topiramate or a derivative thereof.
申请公布号
EP2968181(A4)
申请公布日期
2016.04.13
申请号
EP20140763925
申请日期
2014.03.14
申请人
APRECIA PHARMACEUTICALS COMPANY
发明人
JACOB, JULES;BEACH, LAUREN;WEST, THOMAS, G.;MONKHOUSE, DONALD, C.;SURPRENANT, HENRY, L.