发明名称 |
COMPOUNDS OF '3-(5-SUBSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF |
摘要 |
Synthesis of the novel compound 3 (3-(5-substituted Oxy-2,4-dinitro-phenyl)-2-oxo-propionic acid ester) to make Pyrroloquinoline quinone (PQQ) and using it for pharmaceutical purposes is described. More specifically, this disclosure relates to synthesizing the PQQ in an efficient method by using a novel intermediate Formula 1 resulting in a shorter process and higher yield of PQQ. A unique process to make sodium compound of PQQ using either sodium hydroxide and/or sodium carbonate is also shown. |
申请公布号 |
EP3004047(A1) |
申请公布日期 |
2016.04.13 |
申请号 |
EP20140733718 |
申请日期 |
2014.06.05 |
申请人 |
ANTHEM BIOSCIENCES PVT LTD |
发明人 |
GAVARA GOVINDA, RAJULU;SAMBASIVAM, GANESH;PUTHIAPARAMPIL, TOM THOMAS;CHANDRAPPA KORAMANGALA, RAVINDRA |
分类号 |
C07C201/08;C07C205/56;C07D471/04 |
主分类号 |
C07C201/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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