发明名称 |
MULTISCALE SPECTRAL NANOSCOPY |
摘要 |
A system and method for non-invasively tracking a particle in a sample is disclosed. The system includes a 2-photon or confocal laser scanning microscope (LSM) and a particle-holding device coupled to a stage with X-Y and Z position control. The system also includes a tracking module having a tracking excitation laser, X-Y and Z radiation-gathering components configured to detect deviations of the particle in an X-Y and Z directions. The system also includes a processor coupled to the X-Y and Z radiation gathering components, generate control signals configured to drive the stage X-Y and Z position controls to track the movement of the particle. The system may also include a synchronization module configured to generate LSM pixels stamped with stage position and a processing module configured to generate a 3D image showing the 3D trajectory of a particle using the LSM pixels stamped with stage position. |
申请公布号 |
EP2874700(A4) |
申请公布日期 |
2016.04.13 |
申请号 |
EP20130820283 |
申请日期 |
2013.07.18 |
申请人 |
THE TRUSTEES OF PRINCETON UNIVERSITY |
发明人 |
YANG, HAW;WELSHER, KEVIN |
分类号 |
A61N5/00;G01N15/14;G01N21/64;G02B21/00 |
主分类号 |
A61N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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