发明名称 |
Device and methods for the immunological identification of cerebrospinal fluid |
摘要 |
The present disclosure relates to detection of the presence or absence of cerebrospinal fluid (CSF) in a sample by the detection of one or more antigens that are enriched in CSF compared to their levels in other bodily fluids. The devices and methods are suitable for the detection of the presence or absence of cerebrospinal fluid in samples of mixed bodily fluids from a wide variety of human populations crossing ethnicity, age, gender, health status and genetic variability. |
申请公布号 |
US9310382(B2) |
申请公布日期 |
2016.04.12 |
申请号 |
US201414491256 |
申请日期 |
2014.09.19 |
申请人 |
Affinimark Technologies, Inc. |
发明人 |
Pieribone Vincent |
分类号 |
G01N33/68;G01N33/53;G01N33/574 |
主分类号 |
G01N33/68 |
代理机构 |
Wood, Phillips, Katz, Clark & Mortimer |
代理人 |
Wood, Phillips, Katz, Clark & Mortimer |
主权项 |
1. A lateral flow immunoassay device for detection of the presence or absence of cerebrospinal fluid (CSF) in a sample, comprising
a sample application region, a sample labeling region comprising a first antibody to a CSF-enriched protein of SEQ ID NO: 13, wherein the first antibody is conjugated to a mobile particle, a sample detection region comprising a second antibody to the CSF-enriched protein of SEQ ID NO: 13, wherein the second antibody is fixed to the sample detection region, and wherein, when said sample contains cerebrospinal fluid, said device displays a detectable band in the sample detection region. |
地址 |
Ellington CO US |