发明名称 Whitening cosmetic
摘要 Compositions, comprising (A) a cysteine derivative represented by the formula (I) or a salt thereof:; wherein X and Y are each independently OR1 or NHR2 wherein R1 and R2 are each independently a hydrogen atom or a C1-22 alkyl group;Z is a hydrogen atom or a C1-22 alkyl group; andW is a C1-22 alkyl group, a C1-22 alkoxy group or a C1-22 alkylamino group, and(B) a whitening agent,are useful for whitening skin and reducing melanin production.
申请公布号 US9308157(B2) 申请公布日期 2016.04.12
申请号 US201414288791 申请日期 2014.05.28
申请人 AJINOMOTO CO., INC. 发明人 Takino Yoshinobu;Okura Fumie;Kuroda Shinji
分类号 A61K8/49;A61K8/36;A61K8/368;A61K8/44;A61K8/60;A61K8/64;A61K8/97;A61Q19/02;A61K31/426 主分类号 A61K8/49
代理机构 Oblon, McClelland, Maier & Neustadt, L.L.P. 代理人 Oblon, McClelland, Maier & Neustadt, L.L.P.
主权项 1. A cosmetic agent, comprising: (A) at least one cysteine compound represented by formula (I) or a salt thereof:wherein X and Y are each independently OR1 or NHR2 wherein R1 and R2 are each independently a hydrogen atom or a C1-22 alkyl group; Z is a hydrogen atom or a C 1-22 alkyl group; and W is a C1-22 alkyl group, a C1-22 alkoxy group or a C 1-22 alkylamino group; and (B) at least one whitening agent, wherein: (A) said at least one cysteine compound or a salt thereof is one or more members selected from the group consisting of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid, a salt of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid, N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester, and a salt of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester; and (B) said at least one whitening agent is one or more members selected from the group consisting of arbutin, cetyl ascorbyl ether, kojic acid, 4-methoxy salicylic acid, chamomilla recutita extract, ellagic acid, linoleic acid, glutathione, tranexamic acid, 4-n-butylresorcinol, and 4-hexylresorcinol.
地址 Tokyo JP