Utilizing time-to-positivity to generate treatment recommendations

摘要

Computerized methods and systems, and computer-readable media having computer-executable instructions embodied thereon, for utilizing a time-to-positivity associated with a blood culture to generate at least one treatment recommendation are provided. Methods according to embodiments of the present invention may include receiving an indication that a blood culture is positive for the presence of a particular bacterium, determining a time-to-positivity for the presence of the bacterium, and automatically generating at least one treatment recommendation utilizing the time-to-positivity. If desired, the method may further include one or more of receiving verification of the indication that the blood culture is positive for the presence of the bacterium in question and communicating the positivity determination as appropriate, e.g., utilizing alerts.

主权项

1. A method for utilizing a time-to-positivity associated with a blood culture to generate treatment recommendations, the method comprising:
receiving an indication that the blood culture is inoculated and an indication of a first time corresponding to a time at which the blood culture is inoculated; receiving an indication that the blood culture is received by a positivity-detecting instrument and an indication of a second time corresponding to a time at which the blood culture is received by the positivity-detecting instrument; at a computing device, receiving, directly from the positivity-detecting instrument, an indication that the blood culture is positive for a presence of a bacterium and an indication of a third time corresponding to a time at which the blood culture generated a positive result for the presence of the bacterium; determining, at a processor of the computing device, the time-to-positivity for the presence of the bacterium to provide a first determined time-to-positivity, wherein the first determined time-to-positivity is a quantity of time to generate a detectable positive indication of the presence of the bacterium, the quantity of time comprising at least one of a difference between the third time and the first time or a difference between the third time and the second time; automatically generating at least two treatment recommendations as a first subset of a plurality of treatment recommendations based on the first determined time-to-positivity, wherein the first subset of the plurality of treatment recommendations based on the first determined time-to-positivity is different from a second subset of the plurality of treatment recommendations based on a second time-to-positivity that is different from the first determined time-to-positivity; and in response to automatically generating the at least two treatment recommendations, automatically generating at least one alert indicating that the at least two treatment recommendations have been generated based on the first determined time-to-positivity.