发明名称 METHOD OF PRODUCING ANTIBIOTIC NANOCAPSULES IN POLUDANUM
摘要 FIELD: pharmaceutics.SUBSTANCE: invention relates to chemical and pharmaceutical industry, and is a method of encapsulating a drug by non-solvent deposition method, characterised by that nanocapsule nuclei used are cephalosporin antibiotics, cladding is poludanum at a ratio of cladding:core 3:1, wherein aqueous poludanum is mixed with cephalosporin antibiotic powder and E472 preparation as a surfactant, with stirring after dissolving components of reaction mixture petroleum ether is added in droplets, obtained suspension of nanocapsules is filtered, washed with petroleum ether and dried.EFFECT: invention provides a simpler and faster process of producing nanocapsules and increases mass output.1 cl, 1 dwg, 4 ex
申请公布号 RU2580287(C1) 申请公布日期 2016.04.10
申请号 RU20140140280 申请日期 2014.10.06
申请人 KROLEVETS ALEKSANDR ALEKSANDROVICH 发明人 KROLEVETS ALEKSANDR ALEKSANDROVICH
分类号 A61K9/51;A61K31/545;B01J13/06;B82B1/00;B82B3/00 主分类号 A61K9/51
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