| 发明名称 |
ABUSE-RESISTANT MUCOADHESIVE DEVICES FOR DELIVERY OF BUPRENORPHINE |
| 摘要 |
The present invention provides abuse deterrent mucoadhesive devices for delivery of buprenorphine. Each device comprises a mucoadhesive layer and a backing layer, and the pH in each layer is selected, such that absorption of buprenorphine is maximized. |
| 申请公布号 |
US2016095821(A1) |
申请公布日期 |
2016.04.07 |
| 申请号 |
US201514704955 |
申请日期 |
2015.05.05 |
| 申请人 |
BioDelivery Sciences International, Inc. |
发明人 |
Finn Andrew;Vasisht Niraj |
| 分类号 |
A61K9/70;A61K31/485;A61K31/4748 |
主分类号 |
A61K9/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An abuse deterrent mucoadhesive device for use in managing pain or opioid dependence, the device comprising:
a mucoadhesive layer comprising an effective amount of buprenorphine buffered to a pH of between about 4.0 and about 6.0; and a backing layer buffered to a pH between about 4.0 and about 4.8. |
| 地址 |
Raleigh NC US |
