发明名称 |
CALIBRATION METHOD FOR PHOTOMETRY |
摘要 |
A method for determining a physical property of a biological sample. The method comprises the steps of: acquiring a set of preliminary calibration signals of a first lot of a reagent using an automatic analyzer with a first photometry module; acquiring a reference set of signals of the first lot of the reagent using a calibration analyzer with a second photometry module; determining a set of module specific components by subtracting the reference set of signals from the preliminary calibration signals; acquiring a lot specific set of signals of a second lot of the reagent using the second photometry module; determining a lot calibration for the first photometry module using the set of module specific components and the lot specific set of signals; acquiring a measurement signal of the biological sample using the first photometry module and the second lot of the reagent; and determining a physical property of the biological sample using the measurement signal and the lot calibration. |
申请公布号 |
US2016097785(A1) |
申请公布日期 |
2016.04.07 |
申请号 |
US201514966804 |
申请日期 |
2015.12.11 |
申请人 |
Roche Diagnostics Operations, Inc. |
发明人 |
Horstmann Martin;Lang Fridl |
分类号 |
G01N33/96;G01N21/75;G01J1/02;G01N35/00 |
主分类号 |
G01N33/96 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method for determining a physical property of a biological sample comprising:
acquiring a set of preliminary calibration signals of a first lot of a reagent using an automatic analyzer according to a calibration protocol, wherein the automatic analyzer acquires the preliminary calibration signals using a first photometry module; acquiring a reference set of signals of the first lot of the reagent using a calibration analyzer according to the calibration protocol, wherein the calibration analyzer acquires the reference set of signals using a second photometry module; determining a set of module specific components by subtracting the reference set of signals from the preliminary calibration signals; acquiring a lot specific set of signals of a second lot of the reagent using the second photometry module according to the calibration protocol; determining a lot calibration for the first photometry module using the set of module specific components and the lot specific set of signals; acquiring a measurement signal of the biological sample using the first photometry module and the second lot of the reagent; and determining a physical property of the biological sample using the measurement signal and the lot calibration. |
地址 |
Indianapolis IN US |