发明名称 CALIBRATION METHOD FOR PHOTOMETRY
摘要 A method for determining a physical property of a biological sample. The method comprises the steps of: acquiring a set of preliminary calibration signals of a first lot of a reagent using an automatic analyzer with a first photometry module; acquiring a reference set of signals of the first lot of the reagent using a calibration analyzer with a second photometry module; determining a set of module specific components by subtracting the reference set of signals from the preliminary calibration signals; acquiring a lot specific set of signals of a second lot of the reagent using the second photometry module; determining a lot calibration for the first photometry module using the set of module specific components and the lot specific set of signals; acquiring a measurement signal of the biological sample using the first photometry module and the second lot of the reagent; and determining a physical property of the biological sample using the measurement signal and the lot calibration.
申请公布号 US2016097785(A1) 申请公布日期 2016.04.07
申请号 US201514966804 申请日期 2015.12.11
申请人 Roche Diagnostics Operations, Inc. 发明人 Horstmann Martin;Lang Fridl
分类号 G01N33/96;G01N21/75;G01J1/02;G01N35/00 主分类号 G01N33/96
代理机构 代理人
主权项 1. A method for determining a physical property of a biological sample comprising: acquiring a set of preliminary calibration signals of a first lot of a reagent using an automatic analyzer according to a calibration protocol, wherein the automatic analyzer acquires the preliminary calibration signals using a first photometry module; acquiring a reference set of signals of the first lot of the reagent using a calibration analyzer according to the calibration protocol, wherein the calibration analyzer acquires the reference set of signals using a second photometry module; determining a set of module specific components by subtracting the reference set of signals from the preliminary calibration signals; acquiring a lot specific set of signals of a second lot of the reagent using the second photometry module according to the calibration protocol; determining a lot calibration for the first photometry module using the set of module specific components and the lot specific set of signals; acquiring a measurement signal of the biological sample using the first photometry module and the second lot of the reagent; and determining a physical property of the biological sample using the measurement signal and the lot calibration.
地址 Indianapolis IN US