发明名称 |
SRM ASSAYS TO CHEMOTHERAPY TARGETS |
摘要 |
Quantitative analysis of proteins that are targets of chemotherapy by Selected reaction monitoring (SRM)/Multiple Reaction Monitoring (MRM) mass spectrometry, by measuring modified forms of disclosed specific peptides from the ENT1, ERCC1, FOLR1, RRM1, TUBB3, TOP01, and/or TOP02A proteins. These peptides can be quantified if a modified form thereof comprises a phosphorylated, tyrosine, threonine, serine, and/or other amino acid residues within their amino acid sequence. Biological samples that have been fixed in formalin are used for the analysis. |
申请公布号 |
WO2016004233(A3) |
申请公布日期 |
2016.04.07 |
申请号 |
WO2015US38874 |
申请日期 |
2015.07.01 |
申请人 |
EXPRESSION PATHOLOGY, INC. |
发明人 |
KRIZMAN, DAVID, B.;HEMBROUGH, TODD;THYPARAMBIL, SHEENO;LIAO, WEI-LI;AN, EUNKYUNG |
分类号 |
G01N33/48;G01N31/00;G01N33/50;H01J49/00 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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