发明名称 |
COMPOSITIONS AND METHODS FOR PEPTIDE EXPRESSION AND PURIFICATION USING A TYPE lll SECRETION SYSTEM |
摘要 |
Disclosed are compositions and methods for expressing and purifying a peptide of interest using a Flagellar Type III secretion system. Disclosed are nucleic acid sequences that contain a FlgM nucleic acid sequence, a cleavage site, and a nucleic acid sequence of interest. Also disclosed are polypeptides that contain FlgM, a cleavage site and a peptide of interest. Methods of producing polypeptides that have FlgM, a cleavage site and a peptide of interest are provided. |
申请公布号 |
EP2855676(A4) |
申请公布日期 |
2016.04.06 |
申请号 |
EP20130798228 |
申请日期 |
2013.05.30 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
HUGHES, KELLY, T.;OLIVERA, BALDOMERO, M. |
分类号 |
C12N15/04;C07K14/255;C07K14/435;C12N15/62;C12N15/74 |
主分类号 |
C12N15/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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