发明名称 |
NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED POLYVINYLPYRROLIDONE-BASED POLYMERS, AND COMPOSITIONS, MEDICAL DEVICES, AND USES THEREOF |
摘要 |
Disclosed is a nitric oxide-releasing polyvinylpyrrolidone-based polymer derived from N-vinylpyrrolidone monomer and at least one nitric oxide releasing N2O2− group, in which the N2O2− group is attached to a 2 pyrrolidinone group or a group derived therefrom in the N-vinylpyrrolidone monomer, and the polymer is optionally in combination with a substrate. The NO-releasing polymer can be part of a medical device or pharmaceutical composition and is useful for treating a biological disorder, such as healing a wound, restenosis, and/or promoting angiogenesis. |
申请公布号 |
EP2875056(A4) |
申请公布日期 |
2016.04.06 |
申请号 |
EP20130819293 |
申请日期 |
2013.07.17 |
申请人 |
THE U.S.A. AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
HRABIE, JOSEPH A.;KEEFER, LARRY K. |
分类号 |
C08F26/10;A61B5/00;A61K8/81;A61K31/79;C08F226/10 |
主分类号 |
C08F26/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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