| 发明名称 | Peptide inhibiting matrix metalloproteanases activity and use thereof | ||
| 摘要 | A peptide inhibiting a matrix metalloproteinase activity, thereby improving the condition of skin and a composition containing the peptide is described, where the peptide comprises an amino acid sequence represented by the formula: Xaa1-Xaa2-Pro-Cys-Xaa3-Xaa4-Xaa5-Ser-Xaa6and has excellent bioactivities of inhibiting the activity of hyaluronic acid degrading enzymes, adipogenesis in fat cells, angiogenesis, and the like, thereby being useful for the treatment of various disease such as obesity, cancer, and inflammation. | ||
| 申请公布号 | US9303064(B2) | 申请公布日期 | 2016.04.05 |
| 申请号 | US201114343850 | 申请日期 | 2011.11.02 |
| 申请人 | CAREGEN CO., LTD. | 发明人 | Chung Young Ji;Kim Eun Mi |
| 分类号 | A61K38/00;A61K38/08;A61K8/64;A61K31/728;A61Q19/00;A61Q19/02;A61Q19/06;A61Q19/08;C07K7/06 | 主分类号 | A61K38/00 |
| 代理机构 | Vorys, Sater, Seymour & Pease LLP | 代理人 | Vorys, Sater, Seymour & Pease LLP |
| 主权项 | 1. A peptide inhibiting a matrix metalloproteinase activity, consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. | ||
| 地址 | Gyeonggi-do KR | ||