发明名称 composto diaciletilenodiamina
摘要 [Problem] A compound which is useful as an anti-obesity agent is provided. [Means for Solution] The present inventors have investigated a compound having a DGAT1 inhibitory action, which is promising as an active ingredient of a pharmaceutical composition for treating obesity, type II diabetes mellitus, fatty liver, and diseases associated with these diseases, and as a result, they have found that the diacylethylenediamine compound of the present invention has an excellent DGAT1 inhibitory action, thereby completing the present invention. That is, the diacylethylenediamine compound of the present invention has a DGAT1 inhibitory action, and can be therefore used as an agent for preventing and/or treating obesity, type II diabetes mellitus, fatty liver, and diseases associated with these diseases.
申请公布号 BRPI1013868(A2) 申请公布日期 2016.04.05
申请号 BR2010PI13868 申请日期 2010.04.19
申请人 ASTELLAS PHARMA INC. 发明人 HIROKI FUKUDOME;HIROSHI MORITANI;TAKAHIRO NIGAWARA;TAKESHI HANAZAWA;TOMOAKI KAWANO;YASUHIRO YONETOKU
分类号 A61K31/36;A61K31/343;A61K31/351;A61K31/357;A61K31/381;A61K31/40;A61K31/402;A61K31/4035;A61K31/404;A61K31/41;A61K31/415;A61K31/421;A61K31/4245;A61K31/425;A61K31/427;A61K31/428;A61K31/4365;A61K31/439;A61K31/44;A61K31/445;A61K31/451;A61K31/4535;A61K31/4545;A61K31/455;A61K31/47;A61K31/495;A61K31/4985;A61K31/505;A61K31/5375;A61P1/16;A61P3/04;A61P3/10;A61P43/00;C07C235/46;C07C235/84;C07C237/34;C07C255/46;C07C275/26;C07C275/28;C07C307/06;C07C311/51;C07C317/44;C07C323/62;C07D207/06;C07D209/08;C07D209/42;C07D209/44;C07D211/16;C07D211/34;C07D211/44;C07D211/60;C07D213/81;C07D213/82;C07D215/48;C07D217/26;C07D231/22;C07D239/42;C07D241/04;C07D257/04;C07D263/32;C07D263/34;C07D263/48;C07D271/06;C07D271/10;C07D275/02;C07D277/20;C07D277/56;C07D277/68;C07D295/14;C07D295/18;C07D295/20;C07D307/79;C07D309/06;C07D317/46;C07D319/18;C07D333/38;C07D333/54;C07D333/68;C07D333/70;C07D451/02;C07D495/04 主分类号 A61K31/36
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