| 摘要 |
Isolated metabolites of (1R-trans)-N-[[2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]-methyl]propanamide and pharmaceutical compositions containing such metabolites are described, as well as their use in the manufacture of a medicament for the treatment of a circadian rhythm disorder, a disorder with a circadian component, a sleep disorder, jet lag, shift worker sleep, general anxiety disorder, major depressive disorder, seasonal affective disorder, attention deficit/hyperactivity disorder, Alzheimers Disease, Angelman Syndrome, bipolar disorder, schizophrenia, autism, epilepsy, migraine, night time hypertension, obesity, type 2 diabetes, or testosterone insufficiency. |
