发明名称 CANCER TREATMENT UTILIZING SP-141 TO BIND WITH MDM2 AND ACT AS AN INHIBITOR OF MDM2 EXPRESSION
摘要 An SP-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise SP-141, which comprises 6-methoxy-1-(naphthalen-1-yl)-9 H-pyrido[3,4-b]indote. The compound inhibits expression of oncogenes such as the Mouse Double Minute 2 protein. The compound can bind directly to Mouse Double Minute 2 to inhibit cancer growth including breast cancer growth.
申请公布号 WO2016049453(A1) 申请公布日期 2016.03.31
申请号 WO2015US52216 申请日期 2015.09.25
申请人 TEXAS TECH UNIVERSITY SYSTEM;ZHANG, RUIWEN;WANG, WEI 发明人 ZHANG, RUIWEN;WANG, WEI
分类号 C07D471/04;A61K45/06 主分类号 C07D471/04
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