发明名称 Crystalline Forms of an NK-1 Antagonist
摘要 The present invention is related to crystalline forms of 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide which is an NK-1 antagonist useful in the treatment of induced vomiting and other disorders.
申请公布号 US2016090359(A1) 申请公布日期 2016.03.31
申请号 US201514865370 申请日期 2015.09.25
申请人 Helsinn Healthcare SA 发明人 Bacilieri Christian;Frasca Gionata
分类号 C07D213/75 主分类号 C07D213/75
代理机构 代理人
主权项 1. A non-solvated crystalline free-base form of the compound 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide which is Form I.
地址 Pazzallo-Lugano CH