发明名称 |
SYNTHETIC ARCHAEAL GLYCOLIPID ADJUVANTS |
摘要 |
Archaeal lipid adjuvants are synthesized by chemically coupling various carbohydrates or anionic polar groups to the free hydroxyl(s) of archaeal lipid cores. Chemically stable lipid cores such as saturated archaeol and caldarchaeol are obtained from appropriate Archaea. Archaeosome lipid vesicles are formulated from the synthetic lipids selected to serve as antigen carriers that target antigen-presenting cells and promote an appropriate immune response to the antigen. |
申请公布号 |
EP1999137(B1) |
申请公布日期 |
2016.03.30 |
申请号 |
EP20070719462 |
申请日期 |
2007.03.30 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
SPROTT, DENNIS;WHITFIELD, DENNIS;KRISHNAN, LAKSHMI |
分类号 |
C07H15/06;A61K9/127;A61K39/39;A61K47/24;A61K47/26;A61K47/28;A61P31/00;A61P35/00 |
主分类号 |
C07H15/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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