| 主权项 |
1. In combination a vascular hole closure device and a delivery instrument for delivering the vascular hole closure device to a target site, the combination comprising:
a vascular hole closure device having a covering member at a distal end for positioning internal of a vessel, a first retainer for positioning external of the vessel, a first flexible member extending between the covering member and first retainer and a first engagement member at a proximal portion of the flexible member; and a delivery instrument including a housing having a first stop, the first engagement member engageable with the first stop and overriding the first stop when a predetermined proximal force is applied to the delivery instrument, wherein proximal movement of the delivery instrument in a direction away from the covering member advances the first retainer toward the covering member, wherein the housing of the delivery instrument includes a lumen in which the first engagement member travels during delivery, and the first stop comprises an abutment member in the form of a projecting surface extending transversely of the lumen, wherein the delivery instrument includes a cutting member to sever the first flexible member upon delivery of the closure device to a surgical site. |
