摘要 |
FIELD: medicine.SUBSTANCE: present invention relates to imidazooxazine compound of formula (I) or a salt thereof, wherein A, B, C and D represent N or C-R, N atom, or C-R, N atom, or C-R, and N or C-Rrespectively; R, R, Rand Rare identical or different from each other and each represents hydrogen, halogen, cyano, C-alkyl which may contain a hydroxyl group(s) as a substitute(s), Calkoxy carbonyl, comprising hydroxyl, amino or mono- or di- (Calkoxy) amino as substitutes, optionally substituted mono- or di (Calkyl) aminocarbonyl or pyrazo≤ Rrepresents phenyl, pyridyl or thienyl; and Rand Rare identical or different from each other and each represents hydrogen, hydroxy, Calkyl or Ccycloalkyl.EFFECT: obtaining a pharmaceutical composition based on said compounds, having antitumor activity, AKT inhibitor, method of treating and preventing cancer and use of said compounds for preparing an anticancer agent.12 cl, 6 tbl, 64 ex |