发明名称 NEW ARYLATED CAMPHENES, METHODS FOR PRODUCING AND USING THEM
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to compounds specified in the following list: methyl-2-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-carboxylate; methyl-2-(2,6-dimethoxy-4-pentylphenyl)-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-carboxylate; 2-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-1,7,7-trimethylbicyclo[2.2.1]hept-2-e≠ (2-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-yl)methanol; (2-(2,6-dimethoxy-4-pentylphenyl)-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-yl)methanol; 2-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-carboxylic acid; 2-(2,6-dimethoxy-4-pentylphenyl)-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-carboxylic acid; 3-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-1,7,7-trimethylbicyclo[2.2.1]hept-2-e≠ 3-(2,6-dimethoxy-4-pentylphenyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-o≠ 3-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-o≠ 3-(2,6-dimethoxy-4-pentylphenyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol; and 3-(2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol, which are bound to CB2 receptor stimulation and which are under the good influence of CB2 receptor stimulation.EFFECT: compounds are applicable for treating a condition specified in inflammation, pain, neurological or neurodegenerative disorders, hepatic diseases, cerebral injuries, atherosclerosis, disorders related to anti-fibrinogen action, inflammatory intestinal disease and nausea or any combination thereof.5 cl, 2 tbl, 8 dwg, 3 ex
申请公布号 RU2578715(C2) 申请公布日期 2016.03.27
申请号 RU20120106897 申请日期 2010.11.18
申请人 JISSUM RISERCH DIVELOPMENT KOMPANI OF DZE KHEBRJUJUNIVERSITI OF IERUSALIM, LTD. 发明人 MECHULAM RAFAEL;MAGID LITAL;SHOKHAMI ESTER;BAB ITAI
分类号 C07C43/215;A61K31/09;A61K31/125;A61K31/192;A61K31/216;A61K31/352;A61P19/00;A61P25/00;A61P25/04;A61P25/28;C07C43/23;C07C49/753;C07C62/34;C07C69/757;C07D311/80 主分类号 C07C43/215
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