| 摘要 |
PROBLEM TO BE SOLVED: To provide a bone defect filling material that initiates a bone rebuilding action as quickly as possible following implantation and that afterward remains in the defect and continues acting to promote bone formation activity until sufficient bone formation has been achieved for the rebuilding of the defect, in which rebuilding a bone with the defect by activation of the innate self-regeneration ability of the bone requires a considerably long period of time.SOLUTION: The present invention provides a cotton-like bone defect filling material comprising biodegradable fibers produced by electrospinning, in which the biodegradable fibers contain 40-60 wt% of calcium phosphate particles and 10 wt% or more of silicon-eluting calcium carbonate particles, with the balance containing 30 wt% or more of poly L-lactic acid resin, and the amount of the poly L-lactic acid resin that is non-crystalline is 75-98%.SELECTED DRAWING: Figure 15 |
