HARVESTING AND PURIFICATION OR PERFUSION YIELDER (HAPPY) DEVICE

摘要

A modular device comprising one or more porous substrate subunits comprising a binding substrate that is capable of interacting with a target biological product, either during, or at the end of a manufacturing cycle; and methods of using the device to harvest or purify a biological product.

主权项

1. A harvesting and purification or perfusion yielding (HAPPY) device comprising:
a top housing subunit and a bottom housing subunit adapted to connect to each other, each comprising a port to facilitate the flow of liquid into and out of the device; at least one substrate subunit having a top and bottom surface, disposed between the top and bottom subunits, wherein the interior cavity of the substrate subunit is defined by a housing wall and wherein the top and bottom subunits comprise a porous mesh material covering; and the interior cavity of the substrate subunit comprises a volume of binding substrate capable of binding a target product.