| 发明名称 |
MASS-SPECTROMETRIC RESISTANCE DETERMINATION BY GROWTH MEASUREMENT |
| 摘要 |
The invention relates to a mass-spectrometric method to determine microbial resistances to antibiotics, in which the microbes are cultured in a medium comprising an antibiotic, and a mass spectrum of the microbes is acquired after they have been cultured. The method is characterized by the fact that any microbial growth taking place during the culture is mass-spectrometrically determined with the aid of a reference substance, which is added in a dosed amount and is co-measured in the mass spectrum, wherein a growth in microbes indicates the resistance to the antibiotic. |
| 申请公布号 |
US2016083769(A1) |
申请公布日期 |
2016.03.24 |
| 申请号 |
US201414892340 |
申请日期 |
2014.04.03 |
| 申请人 |
BRUKER DALTONIK GMBH |
发明人 |
LANGE Christoph;SPARBIER Katrin |
| 分类号 |
C12Q1/04;C12Q1/34;C12Q1/44 |
主分类号 |
C12Q1/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the mass-spectrometric determination of the resistance of microbes, in which the microbes are cultured in a medium comprising an antibiotic, and a mass spectrum MScum of the microbes is acquired after they have been cultured, characterized in that any growth of microbes taking place during the culture is determined with the aid of a reference substance, which is added in dosed amount and also measured in the mass spectrum MScum, wherein microbial growth indicates the resistance to the antibiotic. |
| 地址 |
Bremen DE |
