发明名称 Wnt Antagonist and Methods of Treatment and Screening
摘要 The present invention relates to compositions comprising Wnt antagonists and methods of treating Wnt-associated diseases and disorders, such as cancer, inducing differentiation, and reducing the frequency of cancer stem cells, as well as novel methods of screening for such Wnt antagonists. In particular, the invention discloses soluble FZD, SFRP and Ror receptors and their use.
申请公布号 US2016082079(A1) 申请公布日期 2016.03.24
申请号 US201514842398 申请日期 2015.09.01
申请人 OncoMed Pharmaceuticals, Inc. 发明人 SATYAL Sanjeev H.;Mitra Satyajit Sujit Kumar;Gurney Austin L.
分类号 A61K38/17;C07K14/705;A61K31/282;A61K31/337;A61K31/4745;A61K31/7068;A61K39/395 主分类号 A61K38/17
代理机构 代理人
主权项
地址 Redwood City CA US