| 发明名称 | Antibodies that bind to TL1A and their uses | ||
| 摘要 | The present invention relates to antibodies or fragments thereof that bind to TL1A. More specifically, the present invention relates to an antibody or fragment thereof that binds to TL1A comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 51, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 52, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 53; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 54, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 55 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 56. | ||
| 申请公布号 | US9290576(B2) | 申请公布日期 | 2016.03.22 |
| 申请号 | US201414146566 | 申请日期 | 2014.01.02 |
| 申请人 | GLENMARK PHARMACEUTICALS S.A. | 发明人 | Attinger Antoine;Back Jonathan Albert;Blein Stanislas;Lissilaa Rami;Skegro Darko |
| 分类号 | A61K39/395;C07K16/28;A61K47/48;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Sterne, Kessler, Goldstein & Fox, P.L.L.C. | 代理人 | Sterne, Kessler, Goldstein & Fox, P.L.L.C. ;Shea, Jr. Timothy J.;Heenan Erin |
| 主权项 | 1. An antibody or fragment thereof that binds to TL1A comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 51, a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 52, and a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 53; and comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 54, a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 55, and a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 56. | ||
| 地址 | La Chaux de Fonds CH | ||