| 主权项 |
1. A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of hydrogen, C1-6 alkyl, one amino acid, two amino acids linked together, three amino acids linked together, R3 is selected from the group consisting hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, —C(═O)NH2, —NO2, —NH2, —OH, —N (R15)2, and —SR15; R4, R5, R9, and R14 are each independently selected from the group consisting of hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, —C(═O)NH2, —NO2, —NH2, —OH, —NH(R15), —N (R15)2, and —SR15; R10 is selected from the group consisting of halogen, C1-6 alkyl, C1-6 alkoxy, —C(═O)NH2, —NO2, —NH2, —OH, —NH(R15), —N(R15)2, and —SR15; R11, R12, and R13 are each independently selected from the group consisting of hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, —C(═O)NH2, —NO2, —NH2, —OH,—NH(R15), —N(R15)2, and —SR15; R6 is C1-6 dialkyl amine; R7 is selected from the group consisting of hydrogen and C1-6 alkyl; R8 and R15 are each independently C1-6 alkyl; each R16 is independently hydrogen, —OH, or C1-6 alkoxy; n is an integer from 0 to 4; p is 1 or 3; and the dashed line represents an optional double bond where said double bond has a configuration selected from the group consisting of cis and trans, with the proviso that at least one of R4, R5, R9, and R14 is selected from the group consisting of —NH(R15), —N(R15)2, and —SR15, or R3 is selected from the group consisting of —N(R15)2, and —SR15. |
