| 发明名称 | Compositions containing carboxylic acid-substituted derivatives | ||
| 摘要 | The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change. | ||
| 申请公布号 | US9290436(B2) | 申请公布日期 | 2016.03.22 |
| 申请号 | US201213714136 | 申请日期 | 2012.12.13 |
| 申请人 | Elizabeth Arden, Inc. | 发明人 | Diedrich Falko;Neudecker Birgit;Wieland Eberhard;Lewis, II Joseph A.;DiNardo Joseph C.;Thompson Andrew S.;Kerschen James Alan;Wade Peter C. |
| 分类号 | A61K31/225;C07C59/31;C07C69/95;A61K8/37;A61Q19/00;A61Q19/02;A61Q19/06;A61Q19/08;C07C67/08;C07C67/14;C07C67/28;C07C67/31;C07C69/67;A61K8/67;A61K8/97;A61Q17/04;A61Q19/10;A61Q90/00 | 主分类号 | A61K31/225 |
| 代理机构 | Dorf & Nelson LLP | 代理人 | Dorf & Nelson LLP ;Locke, Esq. Scott D. |
| 主权项 | 1. A composition comprising a compound of general Formula I: wherein R1 is a C2-22 straight or branched substituted alkyl sugar group, and wherein two or more hydroxyl groups within the substituted alkyl sugar group are each independently substituted with a C1-22 carboxylic acid; and at least one additive. | ||
| 地址 | New York NY US | ||