POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME

摘要

Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.

主权项

1. A process comprising contacting a contact lens with a solution comprising a lipid uptake reducing amount of at least one water soluble, crosslinked copolymer under contacting conditions suitable to associate said copolymer with said contact lens; wherein said cross-linked copolymer comprises a plurality of crosslinked primary polymer chains each having a degree of polymerization in the range of about 10 to about 10,000, wherein said cross-linked copolymer does not comprise repeating units comprising a carboxylic acid group bonded directly to the polymer backbone.